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Growth-Related Processes: Yield, Decay, and Hydrolysis

Notes on growth-related processes covering microbial yield, decay, maintenance energy, hydrolysis, and oxygen utilization in treatment systems.

Category: Science

Uploaded by Jordan Mitchell on Apr 23, 2026

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GROWTH-RELATED PROCESSES

Concepts:

Balanced growth: substrate (energy source, carbon source, nutrients, electron

acceptors available). Cells use some substrate electrons for energy production

(consuming electron acceptor) and some for synthesis of new cells.

In general

Energy for cell activities = substrate energy available – energy potential of cells

Yield

consumed substrate

produced mass cell

YIELD

= Y

also

nrate consumptio substrate

rate growth

YIELD

= Y

Electron donor

(COD, NH4, etc)

Nutrients (N, P and

trace elements)

Cells

Electron

Acceptor

O2, NO3,

SO4, etc.

H2O, N2,

H2S, etc.

generally

0 < Y < 1

Units of Y:

Y(mass):e cos glu g

cells g

., g . e

ompound substratec g

) weight dry ( cells g

Y(COD):e cos glu g * 07 . 1

cells g * 42 . 1

consumed COD g

COD cell g

Y(e-):e

COD cell g

Electron equivalent of COD from Oxygen reduction half-reaction:

O2 + 4H+ + 4e-  2H2O

Ratio:e

COD substrate g 8

e

O g 8

e 4

O ) g 32 ( * 1 2 2

Y(e-) = 8*Y(COD)

For glucose:

Y(e-) = 8*(1.42/1.07)*Y(mass) = 10.6 Y(mass)

Where Y(e-) > 1

Factors affecting yield:

Substrate type: Connelly et al found for heterotrophs

Y(amino acids) > Y(sugars, alcohols) > Y(NOM)

Y(autotrophs) < Y(heterotrophs)

0.48 < Y(COD, heterotrophs) < 0.72 (Grady et al)

0.0.06 < Y(COD/N, autotrophs) < 0.35 (Grady et al)

Electron acceptor:

Y(COD, aerobic) > Y(COD, denitrifiers) > Y(COD, fermenters)

Growth Conditions:

Temperature

pH

species of organism

ACTIVITIES THAT DO NOT PRODUCE OR EVEN REDUCE GROWTH:

MAINTENANCE ENERGY, DECAY AND CELL LYSIS, PREDATION

Maintenance energy used for: regeneration of enzymes, membrane integrity,

motility, etc.

Use of Y in COD stoichiometry for cell growth:

COD - (1-Y) O2  Y cell-COD

Check: 1 – (1-Y) = Y

Cells

Debris

Biodegradable

particulates

Soluble

COD

NH4-N,

PO4, etc.

Maintenance energy, decay, predation all reduce yield:

Define “observed yield” = Yobs < Y

Example:

Let Y(COD) = 0.5 g cell COD/g-substrate COD consumed

Suppose 50% of biomass grown is lysed and 70% of lysed COD can be recovered

as substrate.

Yobs = 0.5*Y(COD) + 0.5*Y(COD)*0.7 = 0.25 + 0.35*0.5 = 0.495

(Orig. Growth) (lysed and recovered)

Note that debris are non-viable particulate products of decay and accumulate in

biomass, introducing concept of viable fraction.

KEY PROCESS IN DECAY CYCLE IN TREATMENT SYSTEMS:

HYDROLYSIS

Extracellular enzymes hydrolyze biodegradable particulates to soluble COD.

Factors that affect hydrolysis and recovery of COD

Cell mass (to produce enzymes)

Diffusion of products

Two models for oxygen utilization for full growth-decay cycle:

1. Decay produces either debris or new cells directly (no hydrolysis).

Secondary oxygen utilization in decay step for direct production of cells.

Compartments: external COD source, cells, and debris

COD + O2  cell-COD

Cell-COD + O2  cell-COD + debris-COD

2. Decay produces either debris or biodegradable particulates, followed by

hydrolysis. Oxygen utilization is only in the step soluble COD  cells.

Compartments: substrate COD, cells, debris, and biodegradable particulates.

Soluble COD + O2  cell-COD

Cell-COD  debris-COD + biodegradable particulate-COD

Biodegradable particulate-COD  soluble COD

Advantages of second model.

Accounts for influent particulate and soluble COD

Allows for rapidly and slowly degradable COD

Simplifies oxygen consumption calculation

Probably more realistic.

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